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Valif 20 mg may interact with certain medications, including other ED medications, alpha-blockers, antihypertensives, and HIV protease inhibitors. It's essential to inform your healthcare provider about all medications you are taking to avoid potential interactions.Always follow your healthcare provider's instructions and guidance when taking Valif 20 mg or any other medication. If you have any questions or concerns about Valif 20 mg, discuss them with your doctor or pharmacist.